Article
Variations in testosterone pathway genes and susceptibility to testicular cancer in Norwegian men.
International journal of andrology - 1 Dec 2012
Kristiansen W, Aschim E L, Andersen J M, Witczak O, Fosså S D, Haugen T B
Abstract excerpt
Imbalance between the oestrogen and androgen levels in utero is hypothesized to influence testicular cancer (TC) risk. Thus, variation in genes involved in the action of sex hormones may contribute to variability of an individual's susceptibility to TC. Mutations in testosterone pathway genes may alter the level of testosterone in vivo and hypothetically the risk of developing TC. Luteinizing hormone receptor...
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