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Article

Genetic variations associated with the effect of testicular cancer treatment on gonadal hormones.

Human reproduction (Oxford, England) - 1 Dec 2014

Aschim E L, Oldenburg J, Kristiansen W, Giwercman A, Witczak O, Fosså S D, Haugen T B

Abstract excerpt

STUDY QUESTION: Do genetic variations in the testosterone pathway genes modify the effect of treatment on the levels of testosterone and LH in long-term testicular cancer (TC) survivors (TCSs)? SUMMARY ANSWER: Variations in LH receptor (LHR) and in 5α-reductase II (SRD5A2) genes may modify the effect of TC treatment on testosterone levels, whereas genetic variations in the androgen receptor (AR) may modify the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 25336703
DOI: 10.1093/humrep/deu274

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Source receipt: pubmed, retrieved 7 Sept 2026.

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