Article
Genetic variation in hormone metabolizing genes and risk of testicular germ cell tumors.
Cancer causes & control : CCC - 1 Nov 2008
Figueroa Jonine D, Sakoda Lori C, Graubard Barry I, Chanock Stephen, Rubertone Mark V, Erickson R Loren, McGlynn Katherine A
Abstract excerpt
Testicular germ cell tumors (TGCT) that arise in young men are composed of two histologic types, seminomas and nonseminomas. Risk patterns for the two types appear to be similar and may be related to either endogenous or exogenous hormonal exposures in utero. Why similar risk patterns would result in different histologic types is unclear, but could be related to varying genetic susceptibility profiles. Genetic...
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