Article
Androgen receptor polymorphisms and testicular cancer risk.
Andrology - 1 Jan 2015
Grassetti D, Giannandrea F, Paoli D, Masciandaro P, Figura V, Carlini T, Rizzo F, Lombardo F, Lenzi A, Gandini L
Abstract excerpt
Testicular cancer (TC) is currently the most common malignant solid tumour in Caucasian males aged 15-39 years. Epidemiological evidence suggests that its onset may be due to an imbalance in the action of steroidal sex hormones and their receptors. A faulty androgen receptor signalling pathway can, in fact, cause various male reproductive disorders. The androgen receptor (AR) gene has two polymorphic segments...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
