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Article

Positive regulation by γ-aminobutyric acid B receptor subunit-1 of chondrogenesis through acceleration of nuclear translocation of activating transcription factor-4.

The Journal of biological chemistry - 28 Sept 2012

Takahata Yoshifumi, Hinoi Eiichi, Takarada Takeshi, Nakamura Yukari, Ogawa Shinya, Yoneda Yukio

Abstract excerpt

A view that signaling machineries for the neurotransmitter γ-aminobutyric acid (GABA) are functionally expressed by cells outside the central nervous system is now prevailing. In this study, we attempted to demonstrate functional expression of GABAergic signaling molecules by chondrocytes. In cultured murine costal chondrocytes, mRNA was constitutively expressed for metabotropic GABA(B) receptor subunit-1...

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Source

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Identifiers

PMID: 22879594
DOI: 10.1074/jbc.M112.344051
PMCID: PMC3460433

Genes

ATF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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