Article
The bone morphogenetic protein type Ib receptor is a major mediator of glial differentiation and cell survival in adult hippocampal progenitor cell culture.
Molecular biology of the cell - 1 Aug 2004
Brederlau A, Faigle R, Elmi M, Zarebski A, Sjöberg S, Fujii M, Miyazono K, Funa K
Abstract excerpt
Bone morphogenetic proteins (BMPs) act as growth regulators and inducers of differentiation. They transduce their signal via three different type I receptors, termed activin receptor-like kinase 2 (Alk2), Alk3, or bone morphogenetic protein receptor Ia (BMPRIa) and Alk6 or BMPRIb. Little is known about functional differences between the three type I receptors. Here, we have investigated consequences of...
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