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Genetic ablation of GABA <sub>B</sub> receptors from oligodendrocyte precursor cells protects against demyelination in the mouse spinal cord

2024-05-31

Abstract excerpt

GABAergic signaling and GABA B receptors play crucial roles in regulating the physiology of oligodendrocyte-lineage cells, including their proliferation, differentiation, and myelination. Therefore, they are promising targets for studying how spinal oligodendrocyte precursor cells (OPCs) respond to injuries and neurodegenerative diseases like multiple sclerosis. Taking advantage of the temporally controlled and c...

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Literature Corpus work
254eb3b2-c4ce-5319-ba23-7aecfec65bb6
DOI
10.1101/2024.05.29.596385
Open publication

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Genetic ablation of GABA <sub>B</sub> receptors from oligodendrocyte precursor cells protects against demyelination in the mouse spinal cordDOI 10.1101/2024.05.29.596385
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