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Article

Cleft palate is caused by CNS dysfunction in Gad1 and Viaat knockout mice.

PloS one - 19 Mar 2010

Oh Won-Jong, Westmoreland Joby J, Summers Ryan, Condie Brian G

Abstract excerpt

BACKGROUND: Previous studies have shown that disruption of GABA signaling in mice via mutations in the Gad1, Gabrb3 or Viaat genes leads to the development of non-neural developmental defects such as cleft palate. Studies of the Gabrb3 and Gad1 mutant mice have suggested that GABA function could...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20333300
DOI: 10.1371/journal.pone.0009758
PMCID: PMC2841638

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20333300-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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