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Article

AKRs expression in peripheral blood lymphocytes from smokers: the role of body mass index.

Human & experimental toxicology - 1 Apr 2013

Barrón-Vivanco B S, Rothenberg S J, Medina-Díaz I M, Robledo-Marenco L, Rojas-García A E, Hernández-Cadena L, Poblete-Naredo I, Elizondo G, Albores A

Abstract excerpt

Aldo-keto reductases (AKRs) metabolize a wide range of substrates, including polycyclic aromatic hydrocarbons (PAHs), generating metabolites (o-quinones) and reactive oxygen species (ROS), which are capable of initiating and promoting carcinogenesis. Exposure to PAHs, their metabolites, and ROS f...

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PMID: 22872607
DOI: 10.1177/0960327112455071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22872607-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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