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Article

Decreased Aryl Hydrocarbon Receptor Gene Expression and Polymorphic Variants Association with Increase COPD Risk.

International journal of chronic obstructive pulmonary disease - 1 Jan 2025

Sadr Maryam, Asgari Alireza, Assadiasl Sara, Mojtahedi Hanieh, Abdollahi Alireza, Nicknam Mohammad Hossein, Edalatifard Maryam, Soleimanifar Narjes

Abstract excerpt

Background: The Aryl Hydrocarbon Receptor (AHR) is a ligand-activated transcription factor that regulates gene expression, including those involved in metabolizing xenobiotic chemicals. The association of AHR with the onset and severity of Chronic Obstructive Pulmonary Disease (COPD) has not yet been elucidated. This study aimed to investigate the correlation between two AHR polymorphisms and the expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41189718
DOI: 10.2147/COPD.S550884
PMCID: PMC12582520

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships.

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