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Article

Influence of aldo-keto reductase 1C3 polymorphisms in early-onset female psoriasis patients.

Scientific reports - 25 Feb 2023

Nojiri Yuka, Nakamura Motoki, Magara Tetsuya, Yamamoto Aya, Ikumi Kyoko, Nakamura Reiko, Nishida Emi, Haarmann-Stemmann Thomas, Morita Akimichi

Abstract excerpt

The principal pathology of psoriasis is impaired skin barrier function, epidermal thickening, and granular layer loss. Exposure to extrinsic factors such as tobacco smoke and air pollutants is associated with the development of psoriasis. Aryl hydrocarbon receptors (AHRs) are activated by extrinsic factors associated with the development of psoriasis and act as transcriptional regulators. Expression of aldo-keto...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 36841845
DOI: 10.1038/s41598-023-30464-8
PMCID: PMC9968313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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