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Depletion of mboa-7, an enzyme that incorporates polyunsaturated fatty acids into phosphatidylinositol (PI), impairs PI 3-phosphate signaling in Caenorhabditis elegans.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Sept 2012

Lee Hyeon-Cheol, Kubo Takuya, Kono Nozomu, Kage-Nakadai Eriko, Gengyo-Ando Keiko, Mitani Shohei, Inoue Takao, Arai Hiroyuki

Abstract excerpt

Phosphatidylinositol (PI) is a constituent of biomembranes and a precursor of all phosphoinositides (PIPs). A prominent characteristic of PI is that its sn-2 position is highly enriched in polyunsaturated fatty acids (PUFAs), such as arachidonic acid or eicosapentaenoic acid. However, the biologi...

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PMID: 22862955
DOI: 10.1111/j.1365-2443.2012.01624.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22862955-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Depletion of mboa-7, an enzyme that incorporates polyunsaturated fatty acids into phosphatidylinositol (PI), impairs PI 3-phosphate signaling in Caenorhabditis elegans.PMID 22862955Read ↗

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