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Article

The phosphoinositide kinase PIKfyve/Fab1p regulates terminal lysosome maturation in Caenorhabditis elegans.

Molecular biology of the cell - 1 Jul 2006

Nicot Anne-Sophie, Fares Hanna, Payrastre Bernard, Chisholm Andrew D, Labouesse Michel, Laporte Jocelyn

Abstract excerpt

Membrane dynamics is necessary for cell homeostasis and signal transduction and is in part regulated by phosphoinositides. Pikfyve/Fab1p is a phosphoinositide kinase that phosphorylates phosphatidylinositol 3-monophosphate into phosphatidylinositol-3,5-bisphosphate [PtdIns(3,5)P2] and is implicat...

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Source

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Identifiers

PMID: 16801682
DOI: 10.1091/mbc.e05-12-1120
PMCID: PMC1483040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16801682-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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