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Article

Genetic analysis of the myotubularin family of phosphatases in Caenorhabditis elegans.

The Journal of biological chemistry - 5 Sept 2003

Xue Yingzi, Fares Hanna, Grant Barth, Li Zhai, Rose Ann M, Clark Scott G, Skolnik Edward Y

Abstract excerpt

Myotubularins (MTMs) constitute a large family of lipid phosphatases that specifically dephosphorylate phosphatidylinositol (3)P. MTM1 and MTM2 are mutated in X-linked myotubular myopathy and Charcot-Marie-Tooth disease (type 4B), respectively, although the mechanisms whereby MTM dysfunction leads to these diseases is unknown. To gain insight into MTM function, we undertook the study of MTMs in the nematode...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12788949
DOI: 10.1074/jbc.M303259200

Genes

MTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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