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Article

Variation in IL10 and other genes involved in the immune response and in oxidation and prostate cancer recurrence.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2012

Dluzniewski Paul J, Wang Ming-Hsi, Zheng Siqun Lilly, De Marzo Angelo M, Drake Charles G, Fedor Helen L, Partin Alan W, Han Misop, Fallin M Daniele, Xu Jianfeng, Isaacs William B, Platz Elizabeth A

Abstract excerpt

BACKGROUND: To evaluate the association of variation in genes involved in immune response, including IL10, production and detoxification of reactive oxygen species, and repair of oxidative DNA damage with risk of recurrence after surgery for localized prostate cancer. METHODS: We conducted a nested case-control study of men who had a radical prostatectomy in 1993 to 2001. A total of 484 recurrence cases and 484...

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Source

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Identifiers

PMID: 22859398
DOI: 10.1158/1055-9965.EPI-12-0458
PMCID: PMC3467312

Genes

CRP
NOS2
GSTP1
GSR
NOS3
GPX1
IMPACT
MPO
SOD1
SOD2
SOD3
TLR4
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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