Article
Association of polymorphisms in oxidative stress genes with clinical outcomes for bladder cancer treated with Bacillus Calmette-Guérin.
PloS one - 1 Jan 2012
Wei Hua, Kamat Ashish, Chen Meng, Ke Hung-Lung, Chang David W, Yin Jikai, Grossman H Barton, Dinney Colin P, Wu Xifeng
Abstract excerpt
Genetic polymorphisms in oxidative stress pathway genes may contribute to carcinogenesis, disease recurrence, treatment response, and clinical outcomes. We applied a pathway-based approach to determine the effects of multiple single nucleotide polymorphisms (SNPs) within this pathway on clinical outcomes in non-muscle-invasive bladder cancer (NMIBC) patients treated with Bacillus Calmette-Guérin (BCG). We...
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