Article
Prognostic Value of Prostaglandin-endoperoxide Synthase 2 Polymorphisms in Prostate Cancer Recurrence after Radical Prostatectomy.
International journal of medical sciences - 1 Jan 2016
Lee Cheng-Hsueh, Pao Jiunn-Bey, Lu Te-Ling, Lee Hong-Zin, Lee Yung-Chin, Liu Chia-Chu, Huang Chao-Yuan, Lin Victor C, Yu Chia-Cheng, Yin Hsin-Ling, Huang Shu-Pin, Bao Bo-Ying
Abstract excerpt
UNLABELLED: Backgroud: Increasing evidence suggests the involvement of chronic inflammation in the progression of prostate cancer, and prostaglandin-endoperoxide synthase 2 (PTGS2), also known as cyclooxygenase-2, catalyzes the rate-limiting steps of the pathway. We hypothesized that genetic variants of PTGS2 can influence the outcome of prostate cancer patients. METHODS: We genotyped five haplotype-tagging...
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