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Article

Nitric oxide synthase gene polymorphisms and prostate cancer risk.

Carcinogenesis - 1 Apr 2009

Lee Kyoung-Mu, Kang Daehee, Park Sue Kyung, Berndt Sonja I, Reding Douglas, Chatterjee Nilanjan, Chanock Stephen, Huang Wen-Yi, Hayes Richard B

Abstract excerpt

Nitric oxide (NO) induces cytotoxicity and angiogenesis, and may play a role in prostate carcinogenesis, potentially modulated by environmental exposures. We evaluated the association of prostate cancer with genetic polymorphisms in two genes related to intracellular NO: NOS2A [inducible nitric oxide synthase (NOS); -2892T>C, Ex16 + 14C>T (S608L), IVS16 + 88T>G and IVS20 + 524G>A] and NOS3 [endothelial NOS;...

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Identifiers

PMID: 19168583
DOI: 10.1093/carcin/bgp028
PMCID: PMC2664454

Genes

NOS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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