Article
Association of IL-10 polymorphisms with prostate cancer risk and grade of disease.
Cancer causes & control : CCC - 1 Mar 2008
Faupel-Badger Jessica M, Kidd La Creis Renee, Albanes Demetrius, Virtamo Jarmo, Woodson Karen, Tangrea Joseph A
Abstract excerpt
Animal and in vitro models of prostate cancer demonstrate high IL-10 levels result in smaller tumors, fewer metastases, and reduced angiogenesis compared to controls. We sought to examine the hypothesis that genotypes correlated with low IL-10 production may be associated with increased prostate cancer risk among Finnish male participants from the Alpha-tocopherol Beta-carotene Cancer Prevention Study. DNA from...
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