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Article

Human rotavirus-specific IgM Memory B cells have differential cloning efficiencies and switch capacities and play a role in antiviral immunity in vivo.

Journal of virology - 1 Oct 2012

Narváez Carlos F, Feng Ningguo, Vásquez Camilo, Sen Adrish, Angel Juana, Greenberg Harry B, Franco Manuel A

Abstract excerpt

Protective immunity to rotavirus (RV) is primarily mediated by antibodies produced by RV-specific memory B cells (RV-mBc). Of note, most of these cells express IgM, but the function of this subset is poorly understood. Here, using limiting dilution assays of highly sort-purified human IgM(+) mBc,...

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Identifiers

PMID: 22855480
DOI: 10.1128/JVI.01466-12
PMCID: PMC3457288

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22855480-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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