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Article

Phenotypic analysis of T follicular helper and T follicular regulatory cells in primary selective IgM deficiency.

Human immunology - 1 Jan 2000

Kasahara Taissa de M, Bento Cleonice Alves de Melo, Gupta Sudhir

Abstract excerpt

Selective IgM deficiency (SIgMD) is a rare immunodeficiency characterized by serum IgM below two standard of mean, and normal IgG and IgA levels. Both in human and mice with selective IgM deficiency, germinal centers cells are decreased. The development of germinal center and humoral immunity are regulated in part by follicular helper T (TFH) and follicular regulatory T (TFR) cells. However, the analysis of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32773096
DOI: 10.1016/j.humimm.2020.07.008

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