Article
Resistance of murine LTA cells to oncogene--mediated progression from tumorigenic to metastatic phenotype.
Anticancer research - 1 Jan 2000
Tuck A B, Wilson S M, Chambers A F
Abstract excerpt
We have previously shown that expression of the H-ras oncogene alone does not induce progression of a tumorigenic but non-metastatic murine fibroblast cell line (LTA) to a metastatic phenotype. Because myc genes, alone or with ras, have been implicated at different stages of progression in other systems, we examined the ability of v-myc, alone and in combination with H-ras, to induce malignant conversion of LTA....
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