Article
Role of H-ras in the malignant progression of rat tracheal epithelial cells.
Journal of cancer research and clinical oncology - 1 Jan 1994
Cosma G, Hubbard F, Jamasbi R J, Marchok A, Garte S J
Abstract excerpt
The effect of an activated H-ras oncogene on the progression of neoplasia was studied in transformed rat tracheal epithelial cells. Nude mouse tumours produced by injection of these cells exhibited a higher fraction of cells containing the mutant ras gene that did the injected cells, while a subc...
Topics
- Animals
- Cell Transformation, Neoplastic
- Epithelium
- Gene Expression Regulation, Neoplastic
- Genes, ras
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Mutation
- Rats
- Rats, Inbred F344
- Trachea
- Tracheal Neoplasms
- Tumor Cells, Cultured