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Article

Role of H-ras in the malignant progression of rat tracheal epithelial cells.

Journal of cancer research and clinical oncology - 1 Jan 1994

Cosma G, Hubbard F, Jamasbi R J, Marchok A, Garte S J

Abstract excerpt

The effect of an activated H-ras oncogene on the progression of neoplasia was studied in transformed rat tracheal epithelial cells. Nude mouse tumours produced by injection of these cells exhibited a higher fraction of cells containing the mutant ras gene that did the injected cells, while a subclone that lacked the ras mutation was much less tumorigenic than parental cells. Serial passage of one cell line...

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Source

Identifiers

PMID: 7962039
DOI: 10.1007/BF01245374

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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