Article
Spontaneous acquisition of tumorigenicity and invasiveness by mouse lens explant cells during culture in vitro.
In vitro cellular & developmental biology : journal of the Tissue Culture Association - 1 May 1991
Messiaen L, Qian S, De Bruyne G, Boghaert E, Moens T, Rabaey M, Van Roy F, Mareel M
Abstract excerpt
The lens of the eye is one of the rare organs in which tumors do not occur spontaneously. It therefore appeared to us that lens cells would not present the background of spontaneous transformation toward malignancy found with many other cell cultures. We have cultured C3H/HeA mouse lens explant (...
Topics
- Animals
- Cell Division
- Cell Transformation, Neoplastic
- Clone Cells
- Female
- Lens, Crystalline
- Mice
- Mice, Inbred C3H
- Neoplasm Metastasis
- Neoplasm Transplantation
- Neoplasms, Experimental
- Organ Culture Techniques
- Phenotype