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Article

Correction for founder effects in host-viral association studies via principal components.

Statistical applications in genetics and molecular biology - 12 Jul 2012

Reeves Karyn L, McKinnon Elizabeth J, James Ian R

Abstract excerpt

Viruses such as HIV and Hepatitis C (HCV) replicate rapidly and with high transcription error rates, which may facilitate their escape from immune detection through the encoding of mutations at key positions within human leukocyte antigen (HLA)-specific peptides, thus impeding T-cell recognition. Large-scale population-based host-viral association studies are conducted as hypothesis-generating analyses which aim...

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PMID: 22850062
DOI: 10.1515/1544-6115.1827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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