Article
A kinship-based modification of the armitage trend test to address hidden population structure and small differential genotyping errors.
PloS one - 8 Jun 2009
Rakovski Cyril S, Stram Daniel O
Abstract excerpt
BACKGROUND/AIMS: We propose a modification of the well-known Armitage trend test to address the problems associated with hidden population structure and hidden relatedness in genome-wide case-control association studies. METHODS: The new test adopts beneficial traits from three existing testing s...
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