Article
Identifying Cryptic Relationships.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Sun Lei, Dimitromanolakis Apostolos, Chen Wei-Min
Abstract excerpt
Cryptic relationships such as first-degree relatives often appear in studies that collect population samples, including genome-wide association studies (GWAS) and next-generation sequencing (NGS) analyses. Cryptic relatedness not only increases type 1 error rate of association tests but also affects other analytical aspects of GWAS and NGS such as population stratification via principal component analysis. Here,...
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