Article

Pathogen exposure misclassification can bias association signals in GWAS of infectious diseases when using population-based common controls

2022-07-17

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies (GWAS) have been performed to identify host genetic factors for a range of phenotypes, including for infectious diseases. The use of population-based common controls from biobanks and extensive consortiums is a valuable resource to increase sample sizes in the identification of associated loci with minimal additional expense. Non-differential misclassification of t...

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Literature Corpus work: 572d326e-9c53-578d-8d72-071752a00d88
DOI: 10.1101/2022.07.14.22276656

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