Article
Detection of EGFR mutation in tissue samples of non-small-cell lung cancer by a fluorescence polarization assay.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Sept 2012
Liu Wenchao, Li Xiaofei, Zhang Zhipei, Chen Yanan, Qiang Shaoying, Cheng Hong, Fan Li, Liang Ping, Zhang Ju
Abstract excerpt
It is important to identify epidermal growth factor receptor (EGFR) mutations, which have a good value for the individualized management of patients with non-small-cell lung cancer. A novel method for detecting the mutations on exons 19, 21 of EGFR in primary carcinoma samples by a fluorescence polarization (FP) assay was developed in this research. Firstly, 2 pairs of general primers of exons 19, 21 of EGFR...
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