Article
The different clinical significance of EGFR mutations in exon 19 and 21 in non-small cell lung cancer patients of China.
Neoplasma - 1 Jan 2011
Li M, Zhang Q, Liu L, Liu Z, Zhou L, Wang Z, Yue S, Xiong H, Feng L, Lu S
Abstract excerpt
Mutations of epithelial growth factor receptor (EGFR) in exon 19 and 21 are both believed to be associated with carcinogenesis, sensitivity to tyrosine kinase drugs and with the prognosis of non-small cell lung cancers (NSCLCs). However, their exact clinical significance remains disputable. We detected the mutations of 157 NSCLCs from mainland China with high resolution melting analysis and identified exon...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
