Article
A Novel Technique to Detect EGFR Mutations in Lung Cancer.
International journal of molecular sciences - 23 May 2016
Liu Yuanbin, Lei Ting, Liu Zhiyu, Kuang Yanbin, Lyu Jianxin, Wang Qi
Abstract excerpt
Epidermal growth factor receptor (EGFR) gene mutations occur in multiple human cancers; therefore, the detection of EGFR mutations could lead to early cancer diagnosis. This study describes a novel EGFR mutation detection technique. Compared to direct DNA sequencing detection methods, this method is based on allele-specific amplification (ASA), recombinase polymerase amplification (RPA), peptide nucleic acid...
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