Article
Detection of epidermal growth factor receptor mutations in non-small cell lung cancer by immunohistochemistry.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 28 Jan 2021
Yu Xuemei, Mao Ruiqi, Liu Min, Fu Limei, Shi Lifang, Li Xinjun
Abstract excerpt
OBJECTIVES: To evaluate the sensitivity and specificity of immunohistochemistry (IHC) for detecting common epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) and to estimate the cost-effectiveness of IHC testing. METHODS: A total of 208 NSCLC patients were included in the trial, and the EGFR mutation status in the patients were detected by PCR and IHC. Two mutation-specific...
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