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Article

An alternative method for screening EGFR mutation using RFLP in non-small cell lung cancer patients.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Oct 2008

Kawada Ichiro, Soejima Kenzo, Watanabe Hideo, Nakachi Ichiro, Yasuda Hiroyuki, Naoki Katsuhiko, Kawamura Masafumi, Eguchi Keisuke, Kobayashi Koichi, Ishizaka Akitoshi

Abstract excerpt

INTRODUCTION: Epidermal growth factor receptor (EGFR) mutations are strong determinants of tumor response to EGFR tyrosine kinase inhibitors in non-small cell lung cancers (NSCLCs). Currently available methods of EGFR mutation detection rely on direct sequencing. Here, we describe the use of an alternative way to screen EGFR mutations. METHODS: A total of 109 frozen tumor specimens from NSCLC patients were...

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Identifiers

PMID: 18827604
DOI: 10.1097/JTO.0b013e318186fadd

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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