Comprehensive detection of diverse exon 19 deletion mutations of EGFR in lung Cancer by a single probe set.

Abstract excerpt

Detection of exon 19 deletion mutation of EGFR, one of the most frequently occurring mutations in lung cancer, provides the crucial information for diagnosis and treatment guideline in non-small-cell lung cancer (NSCLC). Here, we demonstrate a simple and efficient method to detect various exon 19 deletion mutations of EGFR using a single probe set comprising of an oligo-quencher (oligo-Q) and a molecular beacon...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biosensing Techniques
• Share to Carcinoma, Non-Small-Cell Lung