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Article

The CR3 motif of Rrp44p is important for interaction with the core exosome and exosome function.

Nucleic acids research - 1 Oct 2012

Schaeffer Daneen, Reis Filipa Pereira, Johnson Sean J, Arraiano Cecília Maria, van Hoof Ambro

Abstract excerpt

The 10-subunit RNA exosome is involved in a large number of diverse RNA processing and degradation events in eukaryotes. These reactions are carried out by the single catalytic subunit, Rrp44p/Dis3p, which is composed of three parts that are conserved throughout eukaryotes. The exosome is named for the 3' to 5' exoribonuclease activity provided by a large C-terminal region of the Rrp44p subunit that resembles...

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Identifiers

PMID: 22833611
DOI: 10.1093/nar/gks693
PMCID: PMC3467083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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