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Article

Interactions of human truncated DISC1 proteins: implications for schizophrenia.

Translational psychiatry - 16 Aug 2011

Newburn E N, Hyde T M, Ye T, Morita Y, Weinberger D R, Kleinman J E, Lipska B K

Abstract excerpt

Numerous genetic linkage and association reports have implicated the Disrupted-in-Schizophrenia (DISC1) gene in psychiatric illness. The Scottish family translocation, predicted to encode a C-terminus-truncated protein, suggests involvement of short isoforms in the pathophysiology of mental disorders. We recently reported complex alternative splicing patterns for the DISC1 gene and found that short isoforms are...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 22832604
DOI: 10.1038/tp.2011.31
PMCID: PMC3309510

Genes

DISC1
FEZ1
NDEL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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