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Article

Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.

Biological psychiatry - 15 Feb 2019

Wilkinson Brent, Evgrafov Oleg V, Zheng DongQing, Hartel Nicolas, Knowles James A, Graham Nicholas A, Ichida Justin K, Coba Marcelo P

Abstract excerpt

BACKGROUND: Disrupted in schizophrenia 1 (DISC1) has been implicated in a number of psychiatric diseases along with neurodevelopmental phenotypes such as the proliferation and differentiation of neural progenitor cells. While there has been significant effort directed toward understanding the function of DISC1 through the determination of its protein-protein interactions within an in vitro setting, endogenous...

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Source

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Identifiers

PMID: 29961565
DOI: 10.1016/j.biopsych.2018.05.009
PMCID: PMC6251761

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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