Article
The roles of the iodothyronine deiodinases in mammalian development.
Thyroid : official journal of the American Thyroid Association - 1 Aug 2005
Galton Valerie Anne
Abstract excerpt
The thyroid hormones (TH) are essential for normal development in vertebrate species. This review considers the roles that the three deiodinases, types 1, 2 and 3 (D1, D2, and D3), play in regulating intracellular levels of TH during this critical period. The focus is on rodents and humans with emphasis on brain development. There is little evidence to suggest that the D1 plays a significant role in development...
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