Article
Expression of BRAF V600E mutant protein in epithelial ovarian tumors.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Mar 2013
Preusser Matthias, Capper David, Berghoff Anna S, Horvat Reinhard, Wrba Fritz, Schindl Monika, Schoppmann Sebastian F, von Deimling Andreas, Birner Peter
Abstract excerpt
BACKGROUND: Genetic analyses have identified BRAF V600E mutations in a subset of ovarian carcinomas. The aim of this study was to investigate the expression of BRAF V600E aberrant protein using a novel mutation-specific antibody in epithelial ovarian tumors. METHODS: We immunohistochemically analyzed expression of V600E-mutant BRAF protein in archival formalin-fixed, paraffin-embedded tissue specimens of 142...
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