Article
Inferences from genomic models in stratified populations.
Genetics - 1 Oct 2012
Janss Luc, de Los Campos Gustavo, Sheehan Nuala, Sorensen Daniel
Abstract excerpt
Unaccounted population stratification can lead to spurious associations in genome-wide association studies (GWAS) and in this context several methods have been proposed to deal with this problem. An alternative line of research uses whole-genome random regression (WGRR) models that fit all markers simultaneously. Important objectives in WGRR studies are to estimate the proportion of variance accounted for by the...
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