A unified association analysis approach for family and unrelated samples correcting for stratification.

Abstract excerpt

There are two common designs for association mapping of complex diseases: case-control and family-based designs. A case-control sample is more powerful to detect genetic effects than a family-based sample that contains the same numbers of affected and unaffected persons, although additional markers may be required to control for spurious association. When family and unrelated samples are available, statistical...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Computer Simulation
• Share to Data Interpretation, Statistical