Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRCA1, TP53, and CHEK2 germline mutations in uterine serous carcinoma

18 Jul 2012

Abstract excerpt

BACKGROUND: Uterine serous carcinoma (USC) is not recognized as part of any defined hereditary cancer syndrome, and its association with hereditary breast and ovarian carcinoma and Lynch syndrome are uncertain. METHODS: Using targeted capture and massively parallel genomic sequencing, 151 subjects with USC were assessed for germline mutations in 30 tumor suppressor genes, including BRCA1 (breast cancer 1, early...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA gene mutations in cancer
Share to Breast Cancer Treatment Studies
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22811390
DOI: 10.1002/cncr.27720

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRCA1, TP53, and CHEK2 germline mutations in uterine serous carcinomaPMID 22811390Read ↗

Germline mutations of the DNA repair pathways in uterine serous carcinoma.Semantic proximity Read ↗

Uterine serous carcinoma and germline genetic testing: patterns of referral, completion and pathogenic variant detection.Semantic proximity Read ↗

Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma.Semantic proximity Read ↗

BRCA germline mutations in women with uterine serous carcinoma--still a debate.Semantic proximity Read ↗

Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses.Semantic proximity Read ↗

Identification of two poorly prognosed ovarian carcinoma subtypes associated with CHEK2 germ-line mutation and non-CHEK2 somatic mutation gene signatures.Semantic proximity Read ↗

Low BRCA1 and BRCA2 Germline Mutation Rates in a French-Canadian Population with a Diagnosis of Epithelial Tubo-Ovarian Carcinoma.Semantic proximity Read ↗

Germline multi-gene hereditary cancer panel testing in an unselected endometrial cancer cohort.Semantic proximity Read ↗

Identification of potential therapeutic targets by molecular profiling of 628 cases of uterine serous carcinoma.Semantic proximity Read ↗

Cancer Susceptibility Mutations in Patients With Urothelial Malignancies.Semantic proximity Read ↗

Germline BRCA1 and BRCA2 Mutations in Ovarian CancerSemantic proximity Read ↗

Pathogenic germline variants among women with uterine cancer by ancestry: A commercial laboratory collaborative research registry study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.