Article
BRCA germline mutations in women with uterine serous carcinoma--still a debate.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Dec 2010
Lavie Ofer, Ben-Arie Alon, Segev Yakir, Faro Jonathan, Barak Frida, Haya Nir, Auslender Ron, Gemer Ofer
Abstract excerpt
OBJECTIVE: To determine the incidence of BRCA1 and BRCA2 mutations in an enlarged series of uterine serous carcinoma (USC) patients and to determine whether patients with USC are associated with a personal or familial history of breast or ovarian carcinoma. METHODS: A cohort of all consecutive patients with diagnosed USC was identified for 9 years. Family pedigrees were drawn as far back and laterally as...
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