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Article

Germline mutations of the DNA repair pathways in uterine serous carcinoma.

Gynecologic oncology - 1 Apr 2016

Frimer Marina, Levano Kelly S, Rodriguez-Gabin Alicia, Wang Yanhua, Goldberg Gary L, Horwitz Susan Band, Hou June Y

Abstract excerpt

OBJECTIVE: Treatment options are limited for patients with uterine serous carcinoma (USC). Knowledge of USC's somatic mutation landscape is rapidly increasing, but its role in hereditary cancers remains unclear. We aim to evaluate the frequency and characteristics of germline mutations in genes commonly implicated in carcinogenesis, including those within homologous recombination (HR) and mismatch repair (MMR)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27016235
DOI: 10.1016/j.ygyno.2015.12.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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