Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis.

Journal of internal medicine - 1 Jan 2013

Stender S, Frikke-Schmidt R, Nordestgaard B G, Grande P, Tybjaerg-Hansen A

Abstract excerpt

BACKGROUND: Elevated plasma levels of bilirubin, an endogenous antioxidant, have been associated with reduced risk of ischaemic heart disease (IHD) and myocardial infarction (MI). Whether this is a causal relationship remains unclear. OBJECTIVE: We tested the hypothesis that elevated plasma bilirubin is causally related to decreased risk of IHD and MI. DESIGN: We used a Mendelian randomization approach and three...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bilirubin
Share to Confidence Intervals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Denmark

Share to Glucuronosyltransferase

Share to Incidence

Share to Mendelian Randomization Analysis

Share to Myocardial Ischemia

Share to Odds Ratio

Source

Identifiers

PMID: 22805420
DOI: 10.1111/j.1365-2796.2012.02576.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis.PMID 22805420Read ↗

Serum total bilirubin levels and coronary heart disease--Causal association or epiphenomenon?Semantic proximity Read ↗

Bilirubin and Stroke Risk Using a Mendelian Randomization Design.Semantic proximity Read ↗

Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference.Semantic proximity Read ↗

Genetically Raised Circulating Bilirubin Levels and Risk of Ten Cancers: A Mendelian Randomization Study.Semantic proximity Read ↗

Gilbert syndrome, UGT1A1*28 allele, and cardiovascular disease risk: possible protective effects and therapeutic applications of bilirubin.Semantic proximity Read ↗

Causal Associations Between Serum Bilirubin Levels and Decreased Stroke RiskSemantic proximity Read ↗

Identifying Potential Therapeutic Applications and Diagnostic Harms of Increased Bilirubin Concentrations: A Clinical and Genetic Approach.Semantic proximity Read ↗

Exploring the causal pathway from bilirubin to CVD and diabetes in the UK biobank cohort study: Observational findings and Mendelian randomization studies.Semantic proximity Read ↗

Bilirubin as a potential causal factor in type 2 diabetes risk: a Mendelian randomization study.Semantic proximity Read ↗

Serum Bilirubin in the Czech Population - Relationship to the Risk of Myocardial Infarction in Males.Semantic proximity Read ↗

Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses.Semantic proximity Read ↗

Extreme bilirubin levels as a causal risk factor for symptomatic gallstone disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.