Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Serum total bilirubin levels and coronary heart disease--Causal association or epiphenomenon?

Experimental gerontology - 1 Dec 2015

Kunutsor Setor K

Abstract excerpt

Observational epidemiological evidence supports a linear inverse and independent association between serum total bilirubin levels and coronary heart disease (CHD) risk, but whether this association is causal remains to be ascertained. A Mendelian randomization approach was employed to test whether serum total bilirubin is causally linked to CHD. The genetic variant rs6742078--well known to specifically modify...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bilirubin
Share to Causality

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Artery Disease

Share to Genetic Variation

Share to Genotype

Share to Mendelian Randomization Analysis

Share to Odds Ratio

Source

Identifiers

PMID: 26408227
DOI: 10.1016/j.exger.2015.09.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Serum total bilirubin levels and coronary heart disease--Causal association or epiphenomenon?PMID 26408227Read ↗

Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis.Semantic proximity Read ↗

Circulating cholesteryl ester transfer protein and coronary heart disease: mendelian randomization meta-analysis.Semantic proximity Read ↗

Bilirubin as a potential causal factor in type 2 diabetes risk: a Mendelian randomization study.Semantic proximity Read ↗

Exploring the causal pathway from bilirubin to CVD and diabetes in the UK biobank cohort study: Observational findings and Mendelian randomization studies.Semantic proximity Read ↗

Causal association between serum total bilirubin and cholelithiasis: a bidirectional two-sample Mendelian randomization study.Semantic proximity Read ↗

Bilirubin and Stroke Risk Using a Mendelian Randomization Design.Semantic proximity Read ↗

Causal Associations Between Serum Bilirubin Levels and Decreased Stroke RiskSemantic proximity Read ↗

Genetically Raised Circulating Bilirubin Levels and Risk of Ten Cancers: A Mendelian Randomization Study.Semantic proximity Read ↗

Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference.Semantic proximity Read ↗

Circulating total bilirubin and risk of non-alcoholic fatty liver disease in the PREVEND study: observational findings and a Mendelian randomization study.Semantic proximity Read ↗

Smoking Reduces Plasma Bilirubin: Observational and Genetic Analyses in the Copenhagen General Population Study.Semantic proximity Read ↗

Causal effect of gallstone disease on the risk of coronary heart disease or acute myocardial infarction: a Mendelian randomization studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.