Article
Bilirubin and Stroke Risk Using a Mendelian Randomization Design.
Stroke - 1 May 2017
Lee Sun Ju, Jee Yon Ho, Jung Keum Ji, Hong Seri, Shin Eun Soon, Jee Sun Ha
Abstract excerpt
BACKGROUND AND PURPOSE: Circulating bilirubin, a natural antioxidant, is associated with decreased risk of stroke. However, the nature of the relationship between the two remains unknown. We used a Mendelian randomization analysis to assess the causal effect of serum bilirubin on stroke risk in Koreans. METHODS: The 14 single-nucleotide polymorphisms (SNPs) (<10-7) including rs6742078 of uridine...
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