Bilirubin as a potential causal factor in type 2 diabetes risk: a Mendelian randomization study.

doi:10.2337/db14-0228

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Bilirubin as a potential causal factor in type 2 diabetes risk: a Mendelian randomization study.

Diabetes - 1 Apr 2015

Abbasi Ali, Deetman Petronella E, Corpeleijn Eva, Gansevoort Ron T, Gans Rijk O B, Hillege Hans L, van der Harst Pim, Stolk Ronald P, Navis Gerjan, Alizadeh Behrooz Z, Bakker Stephan J L

Abstract excerpt

Circulating bilirubin, a natural antioxidant, is associated with decreased risk of type 2 diabetes (T2D), but the nature of the relationship remains unknown. We performed Mendelian randomization in a prospective cohort of 3,381 participants free of diabetes at baseline (age 28-75 years; women 52.6%). We used rs6742078 located in the uridine diphosphate-glucuronosyltransferase locus as an instrumental variable...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alleles

Share to Bilirubin

Share to Diabetes Mellitus, Type 2

Share to Genetic Predisposition to Disease

Share to Glucuronosyltransferase

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 25368098
DOI: 10.2337/db14-0228
PMCID: PMC4346199

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bilirubin as a potential causal factor in type 2 diabetes risk: a Mendelian randomization study.PMID 25368098Read ↗

Exploring the causal pathway from bilirubin to CVD and diabetes in the UK biobank cohort study: Observational findings and Mendelian randomization studies.Semantic proximity Read ↗

Genetically Raised Circulating Bilirubin Levels and Risk of Ten Cancers: A Mendelian Randomization Study.Semantic proximity Read ↗

Causal association between serum total bilirubin and cholelithiasis: a bidirectional two-sample Mendelian randomization study.Semantic proximity Read ↗

Serum total bilirubin levels and coronary heart disease--Causal association or epiphenomenon?Semantic proximity Read ↗

Bilirubin and Stroke Risk Using a Mendelian Randomization Design.Semantic proximity Read ↗

Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis.Semantic proximity Read ↗

Assessment of causality between serum gamma-glutamyltransferase and type 2 diabetes mellitus using publicly available data: a Mendelian randomization study.Semantic proximity Read ↗

Liver Function and Risk of Type 2 Diabetes: Bidirectional Mendelian Randomization StudySemantic proximity Read ↗

A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans.Semantic proximity Read ↗

Gallstone Disease and Type 2 Diabetes Risk: A Mendelian Randomization StudySemantic proximity Read ↗

Association between type 2 diabetes and autoimmune liver disease: An integrated analysis of Mendelian randomization and clinical samples.Semantic proximity Read ↗

Circulating total bilirubin and risk of non-alcoholic fatty liver disease in the PREVEND study: observational findings and a Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.