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Article

Extreme bilirubin levels as a causal risk factor for symptomatic gallstone disease.

JAMA internal medicine - 8 Jul 2013

Stender Stefan, Frikke-Schmidt Ruth, Nordestgaard Børge G, Tybjærg-Hansen Anne

Abstract excerpt

IMPORTANCE: In individuals without blockage of their bile ducts, levels of plasma bilirubin likely reflect levels of biliary bilirubin; higher biliary bilirubin levels may increase the risk of gallstone disease. OBJECTIVE: To test the hypothesis that a lifelong increase in plasma bilirubin levels is a causal risk factor for symptomatic gallstone disease in the general population. DESIGN, SETTING, AND...

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Identifiers

PMID: 23753274
DOI: 10.1001/jamainternmed.2013.6465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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