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Article

Melanocortin 1 receptor variants: functional role and pigmentary associations.

Photochemistry and photobiology - 1 Jan 2000

Dessinioti Clio, Antoniou Christina, Katsambas Andreas, Stratigos Alexander J

Abstract excerpt

The significance of human cutaneous pigmentation lies in its protective role against sun-induced DNA damage and photocarcinogenesis. Fair skin and red hair are characterized by a low eumelanin to pheomelanin ratio, and have been associated with increased risk of skin cancer. Cutaneous pigmentation is a complex genetic trait, with more than 120 genes involved in its regulation, among which the melanocortin 1...

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Identifiers

PMID: 21749400
DOI: 10.1111/j.1751-1097.2011.00970.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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